A simplified point-of-care testing approach for preeclampsia blood biomarkers based on nanoscale field effect transistors
Thuy Thi Thanh Pham, Duy Phu Tran, Minh Nguyen, Mohamed Taha Amen, Marnie Winter, Clare Whitehead, Justine Toh, Benjamin Thierry
Abstract
and a five order of magnitudes dynamic range. Pilot clinical validation in four preeclamptic pregnancies confirmed that the accuracy and reliability of the FET platform, paving the way for further development to a much-needed point-of-care preeclampsia testing.
Topics & Concepts
Nanoscopic scaleTransistorPoint-of-care testingPreeclampsiaMaterials sciencePoint of careField-effect transistorNanotechnologyMedicineEngineeringElectrical engineeringImmunologyPregnancyNursingBiologyVoltageGeneticsAdvanced biosensing and bioanalysis techniquesPregnancy and preeclampsia studiesExtracellular vesicles in disease