Toll-Like Receptor 4 Regulates Rabies Virus-Induced Humoral Immunity through Recruitment of Conventional Type 2 Dendritic Cells to Lymph Organs
Chen Chen, Chengguang Zhang, Haoqi Li, Zongmei Wang, Yueming Yuan, Ming Zhou, Zhen F. Fu, Ling Zhao
Abstract
Vaccination is the most efficient method to prevent rabies. TLR4, a well-known immune sensor, plays a critical role in initiating innate immune response.
Topics & Concepts
BiologyRabies virusToll-like receptorImmune systemInnate immune systemImmunologyImmunityVirologyRabiesVaccinationHumoral immunityLymphAcquired immune systemTLR4Dendritic cellPsychologyPsychiatryRabies epidemiology and controlViral Infections and Outbreaks ResearchPoxvirus research and outbreaks