Rapid Intact mass based multi-attribute method in support of mAb upstream process development
Carolina Lanter, Malka Lev, Li Cao, Vakhtang V. Loladze
Topics & Concepts
GlycosylationChemistryN-linked glycosylationGlycanMonoclonal antibodyChromatographyImmunoglobulin light chainHeavy chainTandem mass spectrometryCritical quality attributesBiochemistryAntibodyMass spectrometryBiologyGlycoproteinGeneParticle sizeImmunologyPhysical chemistryMonoclonal and Polyclonal Antibodies ResearchViral Infectious Diseases and Gene Expression in InsectsProtein purification and stability