Blockade of IL-1α and IL-1β signaling by the anti-IL1RAP antibody nadunolimab (CAN04) mediates synergistic anti-tumor efficacy with chemotherapy
Camilla Rydberg Millrud, Adnan Deronic, Caitríona Grönberg, Elin Jaensson Gyllenbäck, Karin von Wachenfeldt, G. Forsberg, David Liberg
Topics & Concepts
Tumor microenvironmentCancer researchSignal transductionStromal cellMetastasisMedicineCell biologyImmunologyChemistryBiologyCancerInternal medicineTumor cellsImmune Cell Function and InteractionInflammasome and immune disordersImmune cells in cancer