A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer
Bing Lü, Zhecheng Zhang, Danni Jin, Xiaolei Yuan, Jin Wang, Yue Ding, Yang Wang, Yong Yao
Abstract
New nanoparticles (Y6 NPs) based on the A-DA'D-A fused-ring conjugated small molecule Y6 have been prepared for the combined photothermal and photodynamic therapy of cancer. Y6 NPs show excellent light absorption from 300 to 900 nm, a good photothermal conversion efficiency of 57% and reactive oxygen species generation capability. The high photothermal conversion ability and superior photodynamic activity of Y6 NPs endow them with great potential for cancer therapy.
Topics & Concepts
Photothermal therapyPhotodynamic therapyNanoparticleConjugated systemMaterials scienceNanotechnologySmall moleculeAbsorption (acoustics)MoleculeCancer therapyPhotochemistryCancerChemistryPolymerOrganic chemistryMedicineComposite materialBiochemistryInternal medicineNanoplatforms for cancer theranosticsAdvanced Photocatalysis TechniquesAdvanced Nanomaterials in Catalysis