Litcius/Paper detail

RETRACTED ARTICLE: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion

Xinling Wang, Wei Xu, Gaowei Hu, Shuai Xia, Zhiping Sun, Zezhong Liu, Youhua Xie, Rong Zhang, Shibo Jiang, Lu Lu

2020Cellular and Molecular Immunology173 citationsDOIOpen Access PDF

Abstract

The authors have retracted this article [1]. After the publication of this article, it came to the authors attention that in order to support the conclusions of the study, the authors should have used primary T cells instead of T cell lines. Additionally, there are concerns that the flow cytometry methodology applied here was flawed. These points resulted in the conclusions being considered invalid.

Topics & Concepts

Spike ProteinSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)Spike (software development)2019-20 coronavirus outbreakCoronavirusSars virusBetacoronavirusBiologyComputational biologyMedicineComputer scienceOutbreakPathologyInfectious disease (medical specialty)Software engineeringDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesPhagocytosis and Immune Regulation