NO released <i>via</i> both a Cu-MOF-based donor and surface-catalyzed generation enhances anticoagulation and antibacterial surface effects
Jianwen Zhang, Xianlan Ke, Maotao Huang, Xinyu Pei, Shuai Gao, Dimeng Wu, Junying Chen, Yajun Weng
Abstract
clotting time and inhibited thrombus formation. In summary, for the first time, NO release from the coating was realized by the combined ways of NO donor and catalytic endogenous NO donor. It can not only meet the high NO release rate required for early anticoagulation and antibacterial of the catheter but also maintain normal anticoagulation requirements in the later period.
Topics & Concepts
CoatingChemistryAntithromboticAdhesionSubstrate (aquarium)Antibacterial activityPolyurethaneThermoplastic polyurethaneNuclear chemistryPolymer chemistryOrganic chemistryBacteriaMedicineGeologyOceanographyBiologyCardiologyGeneticsElastomerNanoplatforms for cancer theranostics