SILAC proteomics based on 3D cell spheroids unveils the role of RAC2 in regulating the crosstalk between triple-negative breast cancer cells and tumor-associated macrophages
Yang Guo, Xinxin Deng, Shan Wang, Yuan Yuan, Zhengwang Guo, Huifeng Hao, Yanna Jiao, Pingping Li, Shuyan Han
Topics & Concepts
Stable isotope labeling by amino acids in cell cultureTriple-negative breast cancerCancer researchTumor microenvironmentCrosstalkChemistryBiologyBreast cancerProteomicsCancerTumor cellsBiochemistryGeneticsOpticsPhysicsGeneImmune cells in cancerCancer Cells and MetastasisEpigenetics and DNA Methylation