Advancements in Gold‐Catalyzed Cascade Reactions to Access Carbocycles and Heterocycles: An Overview
Tapas Ghosh, Sayantika Bhakta
Abstract
This review summarizes recent developments (from 2006 to 2022) in numerous important and efficient carbo- and heterocycle generations using gold-catalyzed cascade protocols. Herein, methodologies involve selectivity, cost-effectiveness, and ease of product formation being controlled by the ligand as well as the counter anion, catalyst, substrate, and reaction conditions. Gold-catalyzed cascade reactions covered different strategies through the compilation of various approaches such as cyclization, hydroarylation, intermolecular and intramolecular cascade reactions, etc. This entitled reaction is also useful for the synthesis of spiro, fused, bridged carbo- and heterocycles.
Topics & Concepts
CascadeCombinatorial chemistryIntramolecular forceCatalysisChemistryIntermolecular forceSelectivityLigand (biochemistry)Cascade reactionSubstrate (aquarium)NanotechnologyOrganic chemistryMaterials scienceMoleculeBiochemistryOceanographyGeologyChromatographyReceptorCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis