TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming
Gaëtan Barbet, Priyanka Nair-Gupta, Michael Schotsaert, Stephen T. Yeung, Julien Moretti, Fabian Seyffer, Giorgi Metreveli, Thomas J. Gardner, Angela Choi, Domenico Tortorella, Robert Tampé, Kamal M. Khanna, Adolfo García‐Sastre, J. Magarian Blander
Topics & Concepts
Cross-presentationAntigen processingMHC class IAntigen presentationCell biologyTransporter associated with antigen processingMHC restrictionBiologyCytotoxic T cellMajor histocompatibility complexEndosomePriming (agriculture)CD8Antigen-presenting cellDendritic cellT cellAntigenImmunologyImmune systemIntracellularBiochemistryBotanyIn vitroGerminationImmunotherapy and Immune ResponsesT-cell and B-cell ImmunologyImmune Cell Function and Interaction