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LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity

Doumet Georges Helou, Pedram Shafiei-Jahani, Benjamin P. Hurrell, Jacob D. Painter, Christine Quach, Emily Howard, Omid Akbari

2021Journal of Allergy and Clinical Immunology40 citationsDOIOpen Access PDF

Topics & Concepts

Adoptive cell transferImmunologyInnate lymphoid cellImmune systemCytokineGene knockdownBiologyCancer researchMedicineAcquired immune systemT cellApoptosisBiochemistryIL-33, ST2, and ILC PathwaysEosinophilic EsophagitisAsthma and respiratory diseases
LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity | Litcius