Microenvironment-responsive release of Mg<sup>2+</sup>from tannic acid decorated and multilevel crosslinked hydrogels accelerates infected wound healing
Na Li, Yi Cao, Jingyi Liu, Wen Zou, Manyu Chen, Hongfu Cao, Siyan Deng, Jie Liang, Tun Yuan, Qiguang Wang, Yujiang Fan, Xingdong Zhang
Abstract
Microenvironment-responsive release of Mg 2+ from tannic acid-decorated, multilevel crosslinked hydrogels with ROS scavenging, antibacterial, anti-inflammatory, and tissue regenerative properties for accelerated healing of infected wounds.
Topics & Concepts
Tannic acidSelf-healing hydrogelsCovalent bondAngiogenesisWound healingReactive oxygen speciesImmune systemMaterials scienceChronic woundMicrobiologyChemistryCell biologyBiophysicsCancer researchImmunologyPolymer chemistryBiochemistryBiologyOrganic chemistryWound Healing and TreatmentsSurgical Sutures and AdhesivesHemostasis and retained surgical items