Phyto-Fabricated Cr <sub>2</sub> O <sub>3</sub> Nanoparticle for Multifunctional Biomedical Applications
Hamza Elsayed Ahmed Mohamed, Shakeeb Afridi, Ali Talha Khalil, Tanzeel Zohra, Muhammad Ali, Muhammad Masroor Alam, Aamer Ikram, Zabta Khan Shinwari, Malik Maaza
Abstract
Aim: The biosynthesis of chromium oxide nanoparticles (Cr2O3 NPs), using Hyphaene thebaica as a bioreductant, for assessment of their potential nanomedicinal applications. Materials & methods: Biosynthesized Cr2O3 NPs were characterized by x-ray diffraction, Fourier-transform infrared spectroscopy, energy dispersive x-ray spectroscopy, scanning and transmission electron microscopy, selected area electron diffraction, UV–Vis spectroscopy and ζ-potential measurement. In vitro assays were used to assess the biological properties of Cr2O3 NPs. Results: Nanoparticles with size approximately 25–38 nm were obtained with a characteristic Cr–O vibration at 417 cm-1. A broad spectrum antimicrobial potential and antioxidant nature is reported. Slight inhibition of polio virus and biocompatibility at low doses was observed. Conclusion: We conclude a multifunctional nature of biogenic Cr2O3 NPs.