N-Terminal Finger Stabilizes the S1 Pocket for the Reversible Feline Drug GC376 in the SARS-CoV-2 Mpro Dimer
Elena Arutyunova, Muhammad Bashir Khan, Conrad Fischer, Jimmy Lu, Tess Lamer, Wayne Vuong, Marco J. van Belkum, Ryan T. McKay, D. Lorne Tyrrell, John C. Vederas, Howard S. Young, M. Joanne Lemieux
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyDrugTerminal (telecommunication)DimerCoronavirus disease 2019 (COVID-19)ChemistryD-dimer2019-20 coronavirus outbreakMedicinePharmacologyInternal medicineComputer scienceInfectious disease (medical specialty)TelecommunicationsOrganic chemistryOutbreakDiseaseSARS-CoV-2 and COVID-19 ResearchPARP inhibition in cancer therapyTuberculosis Research and Epidemiology