An inhibitory and beneficial effect of chlorpromazine and promethazine (C + P) on hyperglycolysis through HIF-1α regulation in ischemic stroke
Sichao Guo, Eric Cosky, Fengwu Li, Longfei Guan, Yu Ji, Wenjing Wei, Changya Peng, Xiaokun Geng, Yuchuan Ding
Topics & Concepts
Glucose transporterNicotinamide adenine dinucleotide phosphateNeuroprotectionLactate dehydrogenaseInternal medicineGlucose Transporter Type 1NADPH oxidaseEndocrinologyChemistryBiologyReactive oxygen speciesBiochemistryPharmacologyGLUT1MedicineInsulinOxidase testEnzymeNeurological Disease Mechanisms and TreatmentsCancer, Hypoxia, and MetabolismAdvanced Glycation End Products research