Molecular sandwich-based DNAzyme catalytic reaction towards transducing efficient nanopore electrical detection of antigen proteins
Lebing Wang, Lebing Wang, Shuo Zhou, Yunjiao Wang, Yan Wang, Liqiang Jing, Xiaohan Chen, Daming Zhou, Liyuan Liang, Bohua Yin, Youwen Zhang, Liang Wang, Liang Wang
Abstract
A molecular sandwich-based DNAzyme catalytic reaction is capable of transducing detectable nucleic acids as a substitute for difficult to yield protein detection in complicated biological matrices, in a nanopore.
Topics & Concepts
DeoxyribozymeNanoporeCatalysisChemistryAntigenNanotechnologyCombinatorial chemistryComputational biologyBiophysicsMaterials scienceDNABiologyBiochemistryGeneticsNanopore and Nanochannel Transport StudiesAdvanced biosensing and bioanalysis techniquesFuel Cells and Related Materials