Inhibition of glycolytic activator PFKFB3 suppresses tumor growth and induces tumor vessel normalization in hepatocellular carcinoma
Kenichi Matsumoto, Takehiro Noda, Shogo Kobayashi, Yoshihiro Sakano, Yuki Yokota, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Kunihito Gotoh, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro� Doki, Hidetoshi Eguchi
Topics & Concepts
Cancer researchCD31Tumor microenvironmentCell cultureBiologyHepatocellular carcinomaEndothelial stem cellCell growthTumor progressionApoptosisAngiogenesisCancerIn vitroTumor cellsGeneticsBiochemistryCancer, Hypoxia, and MetabolismHepatocellular Carcinoma Treatment and PrognosisAngiogenesis and VEGF in Cancer