Validation of a zebrafish developmental defects assay as a qualified alternative test for its regulatory use following the ICH S5(R3) guideline
A.M.J. Weiner, Itziar Irijalba, Miguel Gallego, I. Ibarburu, L. Sainz, Felipe Goñi‐de‐Cerio, Celia Quevedo, A. Muriana
Topics & Concepts
GuidelineZebrafishTest (biology)Computational biologyBiologyMedicineReliability engineeringEngineeringGeneticsPathologyPaleontologyGeneEffects and risks of endocrine disrupting chemicalsAnimal testing and alternativesEnvironmental Toxicology and Ecotoxicology