Design and synthesis of 4,5-diphenyl-imidazol-1,2,3-triazole hybrids as new anti-diabetic agents: in vitro α-glucosidase inhibition, kinetic and docking studies
Mohammad Asgari, Maryam Mohammadi‐Khanaposhtani, Zeinab Sharafi, Mohammad Ali Faramarzi, Hossein Rastegar, Ensieh Nasli‐Esfahani, Fatemeh Bandarian, Parviz Ranjbar Rashidi, Rahmatollah Rahimi, Mahmood Biglar, Mohammad Mahdavi, Bagher Larijani
Topics & Concepts
AcarboseChemistryDocking (animal)IC50Stereochemistry1,2,3-TriazoleClick chemistryImidazole1,2,4-TriazoleIn vitroTriazolePyrimidineYeastCombinatorial chemistryEnzymeMedicinal chemistryOrganic chemistryBiochemistryMedicineNursingClick Chemistry and ApplicationsHIV/AIDS drug development and treatmentSynthesis and biological activity