Mice lacking substance P have normal bone modeling but diminished bone formation, increased resorption, and accelerated osteopenia with aging
Liping Wang, Saiyun Hou, Ilya Sabsovich, Tian‐Zhi Guo, Tzuping Wei, Wade S. Kingery
Topics & Concepts
OsteopeniaEndocrinologyInternal medicineBone resorptionCancellous boneBone remodelingCortical boneOsteoclastDeoxypyridinolineBone diseaseOsteoporosisWild typeMedicineChemistryOsteocalcinBone mineralPathologyReceptorMutantGeneAlkaline phosphataseEnzymeBiochemistryNeuropeptides and Animal PhysiologyVitamin K Research StudiesApelin-related biomedical research