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Reward signals in the motor cortex: from biology to neurotechnology

Gérard Derosière, Solaiman Shokur, Pierre Vassiliadis

2025Nature Communications27 citationsDOIOpen Access PDF

Abstract

Over the past decade, research has shown that the primary motor cortex (M1), the brain’s main output for movement, also responds to rewards. These reward signals may shape motor output in its final stages, influencing movement invigoration and motor learning. In this Perspective, we highlight the functional roles of M1 reward signals and propose how they could guide advances in neurotechnologies for movement restoration, specifically brain-computer interfaces and non-invasive brain stimulation. Understanding M1 reward signals may open new avenues for enhancing motor control and rehabilitation. The primary motor cortex (M1) not only drives movement but also responds to rewards. In this Perspective, the authors discuss the functional roles of M1’s reward signals and propose how they could transform neurotechnologies like brain-computer interfaces and brain stimulation for movement recovery.

Topics & Concepts

NeurosciencePrimary motor cortexPerspective (graphical)Brain–computer interfaceMotor cortexBrain stimulationMovement (music)PsychologyMotor learningMotor areaMotor controlStimulationComputer scienceElectroencephalographyArtificial intelligencePhilosophyAestheticsEEG and Brain-Computer InterfacesNeuroscience and Neural EngineeringMuscle activation and electromyography studies
Reward signals in the motor cortex: from biology to neurotechnology | Litcius