Hypermethylation-mediated downregulation of long non-coding RNA MEG3 inhibits osteogenic differentiation of bone marrow mesenchymal stem cells and promotes pediatric aplastic anemia
Huanhuan Li, Xueju Xu, Dao Wen Wang, Yuan Zhang, Jiao Chen, Bai Li, Shufang Su, Linlin Wei, Hongliang You, Yingqi Fang, Yingchao Wang, Yufeng Liu
Topics & Concepts
MEG3DNMT1DNA methylationMethylationMolecular biologyMesenchymal stem cellDownregulation and upregulationCellular differentiationCancer researchEpigeneticsChemistryDNA methyltransferaseBiologyGene expressionCell biologyLong non-coding RNABiochemistryGeneCancer-related molecular mechanisms researchMesenchymal stem cell researchCancer-related gene regulation