Aerobic capacity and telomere length in human skeletal muscle and leukocytes across the lifespan
Danielle Hiam, Cassandra Smith, Sarah Voisin, Joshua Denham, Xu Yan, Shanie Landen, Macsue Jacques, Javier Alvarez‐Romero, Andrew Garnham, Mary N. Woessner, Markus Herrmann, Gustavo Duque, Itamar Levinger, Nir Eynon
Abstract
=0.26, P=0.03). In healthy individuals, age explain most of the variability of LTL and this appears to be independent of individual aerobic capacity. Individuals with longer LTL also have a longer MTL, suggesting that there might be a shared molecular mechanism regulating telomere length.
Topics & Concepts
TelomereAerobic capacitySkeletal muscleAgeingAerobic exerciseCohortSarcopeniaBody mass indexInternal medicineEndocrinologyMedicineBiologyGeneGeneticsTelomeres, Telomerase, and SenescenceMuscle Physiology and DisordersNutrition and Health in Aging