A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
Chin-San Loo, Jovylyn Gatchalian, Yuqiong Liang, Mathias Leblanc, Mingjun Xie, Josephine Ho, Bhargav Venkatraghavan, Diana C. Hargreaves, Ye Zheng
Topics & Concepts
BiologyCRISPRGenomeNon canonicalFunction (biology)GeneticsComputational biologyNucleosomeCell biologyFOXP3Genome editingHistoneGeneImmune systeminterferon and immune responsesImmune Cell Function and InteractionT-cell and B-cell Immunology