A “dual-key-and-lock” DNA nanodevice enables spatially controlled multimodal imaging and combined cancer therapy
Shuzhen Yue, Jiayin Zhan, Xuan Xu, Junpeng Xu, Sai Bi, Jun‐Jie Zhu
Abstract
assessments demonstrate that the DKL-DND with excellent stimuli-responsive ability, biocompatibility, stability and accumulation behaviour was capable of simultaneously affording accurate tumour diagnosis and efficient tumour growth inhibition. This integrated DKL-DND exhibits great promise in constructing self-adaptive nanodevices for multimodal imaging-guided combination therapy.
Topics & Concepts
NanodeviceLock (firearm)Key (lock)Cancer therapyDual (grammatical number)CancerCancer imagingComputer scienceComputational biologyCancer researchNanotechnologyMedicineMaterials scienceBiologyEngineeringInternal medicineMechanical engineeringComputer securityLiteratureArtAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionBacteriophages and microbial interactions