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The use of single-cell multi-omics in immuno-oncology

Anjun Ma, Gang Xin, Qin Ma

2022Nature Communications33 citationsDOIOpen Access PDF

Abstract

Single-cell multi-omics (scMulti-omics) has brought transformative insights into immuno-oncology, demonstrating success in describing novel immune subsets and defining important regulators of antitumor immunity. Here, we give examples of how scMulti-omics has been used in specific tumor studies and discuss how this may develop in the future.

Topics & Concepts

OmicsTransformative learningComputational biologyImmune systemBiologyBioinformaticsMedicineImmunologyPsychologyPedagogySingle-cell and spatial transcriptomicsCAR-T cell therapy researchImmune Cell Function and Interaction