NRG1 fusion-driven tumors: biology, detection, and the therapeutic role of afatinib and other ErbB-targeting agents
Janessa Laskin, Stephen V. Liu, Khaled Tolba, Christoph Heining, Richard F. Schlenk, Parneet Cheema, J. Cadranel, Martin Jones, Alexander Drilon, A. Cseh, Steve Gyorffy, Flavio Solca, M. Duruisseaux
Topics & Concepts
AfatinibNeuregulin 1Cancer researchErbBMedicineFusion geneAdenocarcinomaNeuregulinLung cancerTargeted therapyCancerEpidermal growth factor receptorGeneGefitinibOncologyBiologyInternal medicineReceptorGeneticsLung Cancer Treatments and MutationsHER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer