AAV2.7m8 transduction of stage 2 human retinal organoids induces highly variable responses in innate and inflammatory gene expression and cytokine secretion
Monica M. Sauter, H R Noel, Divya Sinha, Emma Nelson, Mai N. Xiong, David M. Gamm, Curtis R. Brandt
Topics & Concepts
BiologyTransduction (biophysics)Cell biologyInnate immune systemTransgeneChemokineGene deliveryCytokineGenetic enhancementMolecular biologyImmunologyImmune systemGeneGeneticsBiochemistryRetinal Development and DisordersVirus-based gene therapy researchCRISPR and Genetic Engineering