Indocyanine green-loaded porphyrin covalent organic frameworks for photothermal cancer therapy
Simiao Tong, Cheng Li, Kai Wang, Fengshou Wu
Abstract
A porphyrin-based covalent organic framework was synthesized as a platform for loading of indocyanine green. The resulting composites (ICG@COF NPs) exhibited enhanced photostability and superior photothermal effect, which demonstrated remarkable efficacy in tumor ablation in vivo .
Topics & Concepts
Indocyanine greenPorphyrinPhotothermal therapyCovalent bondMaterials scienceCovalent organic frameworkAblationThermal ablationPhotochemistryNanotechnologyChemistryOrganic chemistryMedicineSurgeryInternal medicineCovalent Organic Framework ApplicationsNanoplatforms for cancer theranosticsAdvanced Photocatalysis Techniques