Selective Iodination Enables Anthocyanin Synthesis to Be More General
Jun Hu, Yue Li, Guangkai Wu, Shuer Liang, Zihan Zhao, Jia Liu, Jiali Chen, Guocan Yu, Jianxia Sun, Weibin Bai
Abstract
The current synthesis routes of anthocyanins are relatively complicated, which significantly hinders their development. We optimized the method by introducing a selective iodination reaction and also established a general scheme for preparing anthocyanin diglycosides. This method allows anthocyanin synthesis to require fewer steps and costs. Based on this, we prepared four common anthocyanins and two anthocyanin diglucosides and measured their antioxidant and anti-insulin resistance activities.
Topics & Concepts
AnthocyaninChemistryHalogenationCombinatorial chemistryOrganic chemistryFood sciencePhytochemicals and Antioxidant ActivitiesPhytochemistry and Biological ActivitiesBioactive natural compounds