Acute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target?
Fenghui Ye, Richard F. Keep, Ya Hua, Hugh Garton, Guohua Xi
Abstract
Microthrombi formation in the brain following subarachnoid hemorrhage (SAH) has been recognized and suspected to contribute to cerebral ischemia. A recent study found that ultra-early cerebral micro-thrombosis occured four hours after experimental SAH. The number of thrombotic microvessels correlated with brain-blood barrier disruption and neuronal injury. If acute cerebral micro-thrombi also occur in humans, is it time to develop a therapy with systemic thrombolysis for SAH patients?
Topics & Concepts
Subarachnoid hemorrhageMedicineThrombolysisThrombosisIschemiaIntracranial ThrombosisCardiologyInternal medicineVenous thrombosisMyocardial infarctionIntracranial Aneurysms: Treatment and ComplicationsAcute Ischemic Stroke ManagementTraumatic Brain Injury and Neurovascular Disturbances