Leveraging gene co-regulation to identify gene sets enriched for disease heritability
Katherine M. Siewert, Samuel S. Kim, Douglas Yao, Huwenbo Shi, Alkes L. Price
Topics & Concepts
BiologyGenome-wide association studyGeneGeneticsRegulation of gene expressionGene expressionComputational biologyHeritabilityGene regulatory networkCandidate geneMissing heritability problemTranscriptomeDiseaseBiological pathwayGene expression profilingSingle-nucleotide polymorphismGenotypeMedicinePathologyGenetic Associations and EpidemiologyBioinformatics and Genomic NetworksRNA Research and Splicing