Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth
Ruyu Pi, Yang Yang, Xiaoyi Hu, Hongyi Li, Houhui Shi, Yu Liu, Xi Wang, Tong An, Tianqi Lu, Yuquan Wei, Xia Zhao, Xiawei Wei
Topics & Concepts
mTORC1mTORC2Cancer researchPI3K/AKT/mTOR pathwayOvarian cancerCell growthCancerBiologyMedicineChemistryInternal medicineSignal transductionCell biologyGeneticsImmune cells in cancerCancer Cells and MetastasisReproductive System and Pregnancy