Induced pluripotent stem-cell-derived CD19-directed chimeric antigen receptor natural killer cells in B-cell lymphoma: a phase 1, first-in-human trial
Armin Ghobadi, Veronika Bachanová, Krish Patel, Jae H. Park, Ian W. Flinn, Peter A. Riedell, Carlos Bachier, Catherine Diefenbach, Carol Wong, Cara Bickers, Lilly Wong, Deepa Patel, Jode Goodridge, Matthew Denholt, Bahram Valamehr, Rebecca Elstrom, Paolo Strati
Topics & Concepts
MedicineRituximabRegimenCytokine release syndromeFludarabineChimeric antigen receptorTolerabilityPharmacologyInternal medicineLymphomaCyclophosphamideOncologyAdverse effectImmunologyChemotherapyImmunotherapyCancerCAR-T cell therapy researchImmune Cell Function and InteractionPluripotent Stem Cells Research