Iron-catalyzed (<i>E</i>)-selective hydrosilylation of alkynes: scope and mechanistic insights
Anirban Sen, Tanuja Tewari, Rohit Kumar, C. P. Vinod, Himanshu Sharma, Kumar Vanka, Samir H. Chikkali
Abstract
Low-valent Fe-(0) catalyzes the hydrosilylation of alkynes at 60–120 °C, exhibiting a broad substrate scope and tolerating functional groups. Mechanistic investigations, kinetic studies and DFT suggest that the reaction follows a Chalk–Harrod mechanism.
Topics & Concepts
HydrosilylationCatalysisScope (computer science)ChemistryCombinatorial chemistryOrganic chemistryComputer scienceProgramming languageAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistry