Minisci‐Type Carbamoylation of Azauracils with Oxamic Acids
Changduo Pan, Dongdong Chen, Miao Zeng, Haoyang Tian, Jin‐Tao Yu
Abstract
Abstract A Minisci‐type carbamoylation of azauracils was developed to afford 6‐carbamoyl azauracils in yields up to 94 %. In this transformation, oxamic acids were employed as the carbamoyl radical sources under metal‐free conditions. It features high atom economy, good functional group compatibility and convenient operation.
Topics & Concepts
ChemistryCompatibility (geochemistry)Combinatorial chemistryStereochemistryChemical engineeringEngineeringCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsSulfur-Based Synthesis Techniques