<i>Lactobacillus</i> group and arterial hypertension: A broad review on effects and proposed mechanisms
Danilo Duarte de Assis Gadelha, José Luiz de Brito Alves, Paulo César Trindade da Costa, Mickael Sousa da Luz, Clênia de Oliveira Cavalcanti, Fabrícia França Bezerril, Juliana Franco Almeida, Josiane de Campos Cruz, Marciane Magnani, Camille M. Balarini, Sandra Rodrigues‐Mascarenhas, Valdir A. Braga, Maria do Socorro de França-Falcão
Abstract
Hypertension is the leading risk factor for cardiovascular diseases and is associated with intestinal dysbiosis with a decrease in beneficial microbiota. Probiotics can positively modulate the impaired microbiota and impart benefits to the cardiovascular system. Among them, the emended Lactobacillus has stood out as a microorganism capable of reducing blood pressure, being the target of several studies focused on managing hypertension. This review aimed to present the potential of Lactobacillus as an antihypertensive non-pharmacological strategy. We will address preclinical and clinical studies that support this proposal and the mechanisms of action by which these microorganisms reduce blood pressure or prevent its elevation.