Zeptomolar-level one-pot simultaneous detection of multiple colorectal cancer microRNAs by cascade isothermal amplification
Junyue Chen, Tingting Fan, Yan Chen, Lizhen Ye, Chen Zhang, Feng Liu, Ying� Qin, Ying Tan, Yuyang Jiang
Topics & Concepts
microRNALoop-mediated isothermal amplificationMultiple displacement amplificationPrimer (cosmetics)Molecular beaconMolecular biologyExonuclease IIIPolymerase chain reactionDNADetection limitComputational biologyChemistryCombinatorial chemistryBiologyOligonucleotideBiochemistryChromatographyGeneDNA extractionEscherichia coliOrganic chemistryAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulationRNA Interference and Gene Delivery