Neurosteroids as positive and negative allosteric modulators of ligand-gated ion channels: P2X receptor perspective
Sonja Sivcev, Eva Kudová, Hana Zemková
Topics & Concepts
Neuroactive steroidPregnenolone sulfatePregnanoloneAllosteric regulationGABAA receptorPregnenoloneLigand-gated ion channelChemistryAllosteric modulatorPurinergic receptorIon channelReceptorPharmacologyAllopregnanoloneNicotinic agonistNeuroscienceBiochemistrySteroidBiologyHormoneAdenosine and Purinergic SignalingNeuroscience and Neuropharmacology ResearchNeuroendocrine regulation and behavior