Inhibition mechanism of melanin formation based on antioxidant scavenging of reactive oxygen species
Wencai Fu, Zhifang Wu, Rui Zheng, Na Yin, Fangjie Han, Zhengzheng Zhao, Mengjiao Dai, Dongxue Han, Wei Wang, Li Niu
Abstract
showed that GSH and PG within a certain concentration not only did not affect the hatchability, survival rate and teratogenic rate of zebrafish embryos, but also can significantly inhibit melanin formation in zebrafish embryos. The results of this study have an important guiding significance for the dosage of antioxidants used in the cosmetics and food industries.
Topics & Concepts
MelaninAntioxidantReactive oxygen speciesZebrafishGlutathioneChemistryOxidative stressIn vivoBiochemistryIn vitroOxygenBiologyEnzymeOrganic chemistryBiotechnologyGenemelanin and skin pigmentationPhotoreceptor and optogenetics researchCircadian rhythm and melatonin