Wastewater Testing and Detection of Poliovirus Type 2 Genetically Linked to Virus Isolated from a Paralytic Polio Case — New York, March 9–October 11, 2022
A. Blythe Ryerson, Daniel J. Lang, Mohammed Alazawi, Milagros Neyra, Dustin Hill, Kirsten St. George, Meghan Fuschino, Emily Lutterloh, Bryon Backenson, Samuel Rulli, Patricia Schnabel Ruppert, Jacqueline Lawler, Nancy McGraw, Andrew Knecht, Irina Gelman, Jane R. Zucker, Enoma Omoregie, Sarah Kidd, David Sugerman, Jaume Jorba, Nancy Gerloff, Terry Fei Fan Ng, Adriana Lopez, Nina B. Masters, Jessica Leung, Cara C. Burns, Janell Routh, Stephanie R. Bialek, M. Steven Oberste, Eli S. Rosenberg, 2022 U.S. Poliovirus Response Team, 2022 U.S. Poliovirus Response Team, Bridget J. Anderson, Noelle Anderson, Jed A. Augustine, Megan E. Baldwin, Kelly M. Schiabor Barrett, Ursula Bauer, Andrew Beck, Hanen Belgasmi, Lydia J. Bennett, Achal Bhatt, Debra Blog, Heather Boss, Isaac Ravi Brenner, Barrett Brister, Travis Wayne Brown, Tavora Buchman, James E. Bullows, Kara Connelly, Blaise Cassano, Christina J. Castro, Cynthia Cirillo, G. Cone, Janine Cory, Amina Dasin, Adina de Coteau, Anny DeSimone, Francoise Chauvin, Cynthia Dixey, Kathleen Dooling, Shani Doss, Christopher Duggar, Christopher N. Dunham, Delia Easton, Christina Egan, Brian Emery, Randall English, Nicola Faraci, Hannah E. Fast, G. Stephanie Feumba, N. W. Fischer, Stephen A. Flores, Ann D. Frolov, Halle Getachew, Brittany Gianetti, Alejandro Godinez, Todd Gray, William J. Gregg, Christina Gulotta, Sarah Hamid, Tiffany Hammette, Rafael Harpaz, Lia Haynes Smith, Brianna Hanson, Elizabeth Henderson, Eugene Heslin, Alexandra Hess, Dina Hoefer, Jonathan Hoffman, Lyndsey Hoyt, Scott Hughes, Anna R. Hutcheson, Tabassum Z. Insaf, Christopher Ionta, Stacey Jeffries Miles, Anita Kambhampati, Haley R. Kappus-Kron, Genevieve N. Keys, Michael Kharfen
Abstract
A VDPV is a strain related to the attenuated live poliovirus contained in OPV. VDPV2s are OPV virus strains that are >0.6% divergent (or at least six nucleotide changes) from the OPV2 strain in the complete VP1 genomic region. https://polioeradication.org/wp-content/uploads/2016/09/ Reporting-and-Classification-of-VDPVs_Aug2016_EN.pdf The term PV2, referring to all serotype 2 polioviruses, is used throughout the report to indicate either a confirmed VDPV2 or a type 2 Sabin-like virus that is genetically related to the Rockland County patient. A Sabin-like poliovirus is a poliovirus that is related to one of the Sabin vaccine strains and whose nucleotide sequence in the genome region encoding the VP1 capsid protein differs from the related Sabin strain by 0-5 nucleotides for type 2 or by 0-9 nucleotides, for types 1 and 3. ** Wastewater, also referred to as sewage, includes water from household or building use (e.g., toilets, showers, and sinks) that can contain human fecal waste and water from nonhousehold sources (e.g., rain and industrial use); it does not include open drains or potable water. https://www.cdc.gov/ healthywater/surveillance/wastewater-surveillance/wastewater-surveillance. html#how-wastewater-surveillance-works https://www.cdc.gov/acute-flaccid-myelitis/index.html reaction equipment for public health testing purposes from QIAgen. Nancy McGraw reports an uncompensated leadership in the New York State Association of County Health Officials.