False-Positive Uptake of 123I-MIBG in the Basal Ganglion in a Pediatric Neuroblastoma Patient
Yanfeng Xu, Siqi Li, Xia Lu, Wei Wang, Jigang Yang
Abstract
ABSTRACT: A 7-year-old boy with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT to evaluate the therapy response. The scan revealed abnormal 123 I-MIBG uptake in the left basal ganglion, indicating the possibility of brain metastasis. Subsequent contrast-enhanced brain MRI, however, did not show any abnormal signal intensity in the left basal ganglion. Follow-up 123 I-MIBG SPECT/CT scans at 3-month and 9-month also did not show abnormal MIBG uptake in the same area. The case highlights the possibility of false-positive uptake of 123 I-MIBG in the basal ganglion.
Topics & Concepts
MedicineGanglionNeuroblastomaBasal (medicine)Basal gangliaNuclear medicineRadiologyPathologyInternal medicineCentral nervous systemAnatomyBiologyGeneticsInsulinCell cultureNeuroblastoma Research and TreatmentsGlioma Diagnosis and TreatmentMedical Imaging Techniques and Applications