The development of an electropolymerized, molecularly imprinted polymer (MIP) sensor for insulin determination using single-drop analysis
Tanja Zidarič, David Majer, Tina Maver, Matjaž Finšgar, Uroš Maver
Abstract
= 0.9991), a limit of detection of 1.9 pM, and a limit of quantification of 6.2 pM. The rapid response time to the protein target and the portability of the developed sensor, which is considered a disposable MIP-based system, make this MIP-SPCE sensor a promising candidate for point-of-care applications. In addition, the MIP-SPCE sensor was successfully used to detect insulin in a pharmaceutical sample. The sensor was deemed to be accurate (the average recovery was 108.46%) and precise (the relative standard deviation was 7.23%).
Topics & Concepts
Molecularly imprinted polymerDetection limitMaterials scienceCyclic voltammetryPolypyrroleMolecular imprintingElectrochemical gas sensorAnalyteAnalytical Chemistry (journal)ChromatographyElectrodePolymerChemistryElectrochemistryPolymerizationSelectivityComposite materialCatalysisPhysical chemistryBiochemistryElectrochemical sensors and biosensorsAnalytical chemistry methods developmentAnalytical Chemistry and Sensors