Sanggenol L induces ferroptosis in non-small cell lung cancer cells via regulating the miR-26a-1-3p/MDM2/p53 signaling pathway
Rong Fu, Yujie You, Yuqing Wang, Jue Wang, Yu Lu, Rui Gao, Min Pang, Peng Yang, Hailong Wang, Peng Yang, Hailong Wang
Topics & Concepts
Mdm2Cancer researchUbiquitin ligaseApoptosisLipid peroxidationCancer cellProgrammed cell deathGene silencingReactive oxygen speciesGPX4ChemistryCell biologyDownregulation and upregulationCancerGlutathioneBiologyUbiquitinOxidative stressBiochemistryGlutathione peroxidaseGeneticsEnzymeGeneFerroptosis and cancer prognosisCancer-related molecular mechanisms researchRNA modifications and cancer