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Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery

André Dallmann, Anneke Himstedt, Juri Solodenko, Ibrahim Ince, Georg Hempel, Thomas Eißing

2020Journal of Pharmacokinetics and Pharmacodynamics21 citationsDOI

Topics & Concepts

Physiologically based pharmacokinetic modellingPostpartum periodPregnancyPharmacokineticsMedicinePhysiologyObstetricsDrugPharmacologyBiologyGeneticsPharmaceutical studies and practicesAntibiotics Pharmacokinetics and EfficacyPregnancy and Medication Impact
Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery | Litcius