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The constitutive activation of TLR4-IRAK1- NFκB axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients

Valeria Cordone, Francesca Ferrara, Alessandra Pecorelli, Anna Guiotto, Antonio Vitale, Fernanda Amicarelli, Carlo Cervellati, Joussef Hayek, Giuseppe Valacchi

2022Free Radical Biology and Medicine20 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeMECP2Rett syndromeInflammationPeripheral blood mononuclear cellImmunologyPyroptosisTLR4TLR9Innate immune systemBiologyCaspase 1Cancer researchImmune systemGeneticsGeneGene expressionDNA methylationPhenotypeIn vitroInflammasome and immune disordersGenetics and Neurodevelopmental DisordersToxoplasma gondii Research Studies
The constitutive activation of TLR4-IRAK1- NFκB axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients | Litcius