Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR
Vivek Dhiman, Saranjit Singh, Ankit Balhara, Bhoopendra Singh Kushwah, Laximan Velip, Vijaya Madhyanapu Golla, Gananadhamu Samanthula
Topics & Concepts
ChemistryDegradation (telecommunications)Ammonium acetateChromatographyAcetonitrileAlkaloidDrugForced degradationHydrolysisHigh-performance liquid chromatographyBiochemistryOrganic chemistryPharmacologyTelecommunicationsComputer scienceMedicineQuinazolinone synthesis and applicationsChronic Myeloid Leukemia TreatmentsCancer therapeutics and mechanisms