Acute aerobic exercise enhances cerebrovascular shear-mediated dilation in young adults: the role of cerebral shear
Rintaro Sakamoto, Tatsuki Kamoda, Kohei Sato, Shigehiko Ogoh, Masaki Katayose, Toru Neki, Erika Iwamoto
Abstract
We found that 30-min cycling (target intensity was 80% of the ventilatory threshold) with increasing shear of the internal carotid artery (ICA) enhanced transient hypercapnia-induced shear-mediated dilation of the ICA, reflecting improved cerebrovascular endothelial function. This enhancement of ICA dilation was diminished by suppressing the exercise-induced increase in ICA shear via hyperventilation. Our results indicate that increases in cerebral shear may be a key stimulus for improving cerebrovascular endothelial function after exercise in young adults.
Topics & Concepts
HypercapniaHyperventilationCardiologyInternal carotid arteryMedicineInternal medicineStimulus (psychology)Middle cerebral arteryCerebral blood flowAnesthesiaPsychologyRespiratory systemIschemiaPsychotherapistCardiovascular Health and Disease PreventionCerebrovascular and Carotid Artery DiseasesTraumatic Brain Injury and Neurovascular Disturbances