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Peptide-Derived Biosensors and Their Applications in Tumor Immunology-Related Detection

Minxuan Wang, Lingyun Li, Limin Zhang, Jinge Zhao, Zhenqi Jiang, Weizhi Wang

2021Analytical Chemistry62 citationsDOI

Abstract

Small-molecular targeting peptides possess features of biocompatibility, affinity, and specificity, which is widely applied in molecular recognition and detection. Moreover, peptides can be developed into highly ordered supramolecular assemblies with boosting binding affinities, diverse functions, and enhanced stabilities suitable for biosensors construction. In this Review, we summarize recent progress of peptide-based biosensors for precise detection, especially on tumor-related analysis, as well as further provide a brief overview of the progress in tumor immune-related detection. Also, we are looking forward to the prospective future of peptide-based biosensors.

Topics & Concepts

BiosensorChemistryPeptideComputational biologyNanotechnologySupramolecular chemistryBinding affinitiesMolecular recognitionBiochemistryReceptorBiologyMoleculeOrganic chemistryMaterials scienceAdvanced biosensing and bioanalysis techniquesClick Chemistry and ApplicationsChemical Synthesis and Analysis
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