Dapagliflozin exerts anti-inflammatory effects via inhibition of LPS-induced TLR-4 overexpression and NF-κB activation in human endothelial cells and differentiated macrophages
Elaheh Abdollahi, Fariborz Keyhanfar, Ali‐Akbar Delbandi, Reza Falak, Seyed Javad Hajimiresmaiel, Massoumeh Shafiei
Topics & Concepts
DapagliflozinInflammationUmbilical veinLipopolysaccharideNF-κBPharmacologyProinflammatory cytokineChemistryMacrophageApoptosisBiologyBiochemistryEndocrinologyImmunologyDiabetes mellitusType 2 diabetesIn vitroDiabetes Treatment and ManagementKruppel-like factors researchImmune cells in cancer